News and Announcements

  • February 8, 2024

Introducing GDC 2.0: A New Cohort-Centric Design

The GDC has released GDC 2.0 which expands on the GDC Data Portal initially launched in 2016 by providing a cohort-centric design and new analysis tools. GDC 2.0 features include: Enhanced tools ...
  • December 4, 2023

New TCGA Whole Genome Data and Five New NCI MATCH Projects

GDC Data Release 39 is now available on the GDC Data Portal. Several main features for this release include new TCGA WGS variants and additional higher coverage alignments, and five new projects from ...
  • October 30, 2023

New Other Clinical Attribute Node and Additional TCGA Properties in GDC Data Dictionary

Introducing a new node for incorporating additional clinical attributes, plus new properties and enumerated values to support The Cancer Genome Atlas (TCGA) and other NCI programs in GDC Data ...
  • August 31, 2023

9000+ New TCGA WGS alignments Now Available!

The GDC’s Data Release 38 includes 9000+ high coverage TCGA WGS alignments, data for new CGCI, MATCH, and MP2PRT projects, and a variety of data from other NCI programs: 9000+ high coverage ...
  • June 16, 2023

New GDC Data Dictionary Clinical Properties for TARGET, HCMI, and TCGA

In GDC Data Dictionary Release 2.6.6, the GDC added support for: New Clinical Properties for TARGET, HCMI, and TCGA - Several new properties and enumerated values for diagnosis, treatment, ...
  • May 11, 2023

GDC Legacy Archive Retires

The Genomic Data Commons strives to provide standardized and relevant genomic data to the cancer research community. While data processed according to the most up-to-date pipelines is provided to ...
  • March 29, 2023

New Projects at the GDC: Lung Cancer and MATCH Treatment Arms

The GDC’s Data Release 37 includes four new projects: APOLLO-LUAD - Proteogenomic Characterization of Lung Adenocarcinoma, CGCI-HTMCP-LC - HIV+ Tumor Molecular Characterization of Lung Cancer, and ...
  • February 2, 2023

New TCGA and TARGET Properties and Sample Type Restructuring

In GDC Data Dictionary Release 2.6.0, the GDC added support for: New TCGA and TARGET Properties - Several new properties and enumerated values for diagnosis, treatment, molecular tests, ...
  • December 12, 2022

New Data from NCI’s MATCH and EAGLE Studies Available

GDC Data Release 36 includes WXS and RNA-Seq data for cases from NCI’s MATCH precision medicine clinical trial (MATCH-Z1D; phs001859) and WGS, WXS, and RNA-Seq data for lung adenocarcinoma cases ...
  • September 28, 2022

New TARGET AML RNA-Seq and CPTAC Single Nuclei RNA-Seq Data, Update to Variant Caller Pipeline

New data sets are now available including RNA-Seq data from the TARGET acute myeloid leukemia project and single nuclei RNA-Seq data from the CPTAC program. These changes are summarized below: ...
  • July 27, 2022

New Release of Beat AML Mutations, CPTAC Cases, and Fusion Data

In Data Release 34, the GDC released new data from the Beat AML and Clinical Proteomic Tumor Analysis Consortium (CPTAC) programs: Beat AML - Mutations and MAF files from the BEATAML1.0-COHORT ...
  • July 8, 2022

GDC Now Supports m6A MeRIP-Seq Data and the UICC Tumor Staging System

In GDC Data Dictionary Release 2.5.0, the GDC added support for: MeRIP-Seq Data Submission – Methylated RNA immunoprecipitation sequencing (MeRIP-Seq) characterizes m6A-methylated RNA UICC ...
  • May 3, 2022

Exceptional Responders and MP2PRT: New NCI Projects at the GDC!

In Data Release 33, the GDC released data from two new projects at the GDC: NCI’s Exceptional Responders Initiative, which set out to understand why some patients have unexpected and long- ...
  • March 29, 2022

GDC Gene Model Updated to GENCODE 36

The gene model used as a reference across GDC has been updated from GENCODE 22 to GENCODE 36. GENCODE gene sets are continuously updated to improve the coverage and accuracy. GENCODE 36, which was ...
  • September 23, 2021

Data from Landmark Chernobyl studies, New Methylation Pipeline, and More

Highlights from the GDC's recent Data Release 30 include data from major studies exploring the effects of Chernobyl radiation and methylation arrays processed via a new pipeline at the GDC. The data ...
  • May 12, 2021

Browse Data from Rare Cancers in the Data Portal

A recent data release offers new ways to access data from the Count Me In project. The nonprofit research initiative enables patients in the US and Canada to share their medical information and ...
  • September 8, 2020

Explore MMRF Mutations in the Data Portal

The GDC’s Data Release 26 features updates allowing Multiple Myeloma Research Foundation (MMRF) CoMMpass data to be explored directly in the GDC Data Portal. This behind-the-scenes change enables ...
  • May 7, 2020

New Cases of HIV-Associated Cancers & Head and Neck Cancers Available

The GDC’s latest data release includes two major National Cancer Institute projects: the HIV+ Tumor Molecular Characterization Project (HTMCP) and Cancer Proteomic Tumor Analysis Consortium (CPTAC ...
  • December 10, 2019

Data from AACR Project GENIE Released

The GDC has released data for over 44,000 cases from the American Association for Cancer Research’s Project Genomics Evidence Neoplasia Information Exchange (AACR Project GENIE, phs001337), ...
  • November 5, 2019

New Clinical Data Analysis Tools, Submission Support & Other Updates

In a major update to GDC's Data Portal, users can now plot and explore clinical data in the Analysis area. A new look and feel is also available for searching clinical metadata in the Exploration ...
  • July 1, 2019

Data From the MMRF's Longitudinal Study and Other Projects Released

Data from the Multiple Myeloma Research Foundation (MMRF) is now available at the GDC. This is a major new data set with nearly 1000 patients with extensive molecular and clinical data, including ...
  • March 26, 2019

CPTAC Genomic Data Now Available in the NCI Genomic Data Commons (GDC)

CPTAC has provided the Genomic Data Commons (GDC) with genomic data from cancer patients with diverse disease types including Uterine Corpus Endometrial Carcinoma (UCEC), Clear Cell Renal Cell ...
  • February 20, 2019

GDC DAVE Tools Support Visualization of Controlled Access Somatic Mutations from Foundation Medicine

Users who have been granted access to Foundation Medicine data can now visualize somatic mutations using GDC Data Analysis, Visualization, and Exploration (DAVE) tools. See Release Notes for ...
  • November 7, 2018

Visualize Copy Number Alterations in the GDC Data Portal

The GDC released a new version of the GDC Data Portal with new visualization tools for copy number variations (CNVs). CNVs, categorized as gains and losses, can now be visualized in conjunction with ...
  • September 27, 2018

Diffuse Large B-Cell Lymphoma Data Available in GDC Data Portal

Data from molecular characterization of 574 Diffuse Large B-Cell Lymphoma (DLBCL) biopsy samples is now available in the GDC Data Portal. Published in the New England Journal of Medicine, Schmitz et ...
  • May 23, 2018

The NCI GDC Releases New Slide Image Viewer

The NCI's Genomic Data Commons (GDC) released a new slide image viewing feature in the GDC Data Portal allowing researchers to view, zoom, and pan slide images associated with a case directly through ...
  • November 16, 2017

The NCI GDC Releases New Cohort Comparison Features

The NCI's Genomic Data Commons (GDC) released new features allowing users to build and compare custom cohorts and perform operations on case, gene, or mutation sets. Users are now able to use the new ...
  • October 24, 2017

18,000+ cases of Foundation Medicine (FMI) Single Nucleotide Variants Now Available in the NCI Genomic Data Commons (GDC)

FMI has provided the Genomic Data Commons (GDC) with genomic profiling data from approximately 18,000 adult patients with a diverse array of cancers that underwent genomic profiling using ...
  • September 19, 2017

GDC Webinar: Analyzing Data using GDC Data Analysis, Visualization, and Exploration (DAVE) Tools

The Analyzing Data using GDC Data Analysis, Visualization, and Exploration (DAVE) Tools webinar will help introduce users to GDC tools for analyzing data from cancer genomic studies. As an example, we will explore most frequently mutated genes and mutations and perform a survival analysis for cases with and without these mutations, view the distribution of particular mutations and mutated genes across the GDC and visualize associated transcripts in a protein viewer, build custom gene sets for targeted analysis, perform integrated analysis on the most mutated cases in an OncoGrid, and analyze cases within and across projects.

  • June 29, 2017

The NCI GDC Officially Launched DAVE: Data Analysis, Visualization, and Exploration

The NCI's Genomic Data Commons (GDC) officially launched Data Analysis, Visualization, and Exploration (DAVE) tools transforming the GDC from a cancer genomics data repository into an interactive ...
  • January 17, 2017

GDC Webinar: Querying and Downloading Data using the GDC Data Portal and the GDC Data Transfer Tool

The Querying and Downloading Data using the GDC Data Portal and the GDC Data Transfer Tool webinar will help introduce users to the GDC tools for downloading and retrieving data from cancer genomic studies. As an example, we will query and download open access data using the GDC Data Portal and the high performance GDC Data Transfer Tool. We will also review the process for obtaining access to controlled data and demonstrate how to generate a token for downloading controlled access data.

  • November 4, 2016

GDC Webinar: Navigating the GDC - A Case Study

The Navigating the GDC - A Case Study webinar is the first webinar in a series of NCI GDC Webinar. This webinar will help introduce users to the different GDC tools and data types that are available to support cancer genomic analysis. As an example, we will identify common p53 mutations in colon cancer in the GDC cBioPortal, verify mutation calls using BAM slicing in the GDC Data Portal, and investigate the impact of mutations on RNA-Seq expression. In the process we will also highlight the GDC Data Transfer Tool, harmonized clinical data, and the GDC API.

  • September 28, 2016

NCI Collaborates with Multiple Myeloma Research Foundation

The NCI announced a collaboration with the Multiple Myeloma Research Foundation (MMRF) to integrate MMRF's wealth of genomic and clinical data on the disease into the GDC. The MMRF is the first non- ...
  • June 29, 2016

Foundation Medicine Agreement Will Provide Variant Data to GDC

An agreement between NCI and Foundation Medicine will bring genomic variant data for 18,000 cancer cases to the GDC.
  • June 6, 2016

The NCI GDC Officially Launched by Vice President Joe Biden

The NCI’s Genomic Data Commons (GDC) was officially launched on June 6th at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting by Vice President Joe Biden as part of the National Cancer Moonshot Initiative. The GDC is an interactive data sharing platform that enables the access, standardization, analysis, and submission of cancer genomic data in support of precision medicine. Details about the GDC and support for the National Cancer Moonshot Initiative are available in the NCI Press Release on the GDC Launch.

  • May 19, 2016

The NCI GDC Completes Phase 3 Activities

The NCI’s Genomic Data Commons (GDC) project completes Phase 3 activities. In Phase 3, the GDC generates high level data including DNA-Seq derived germline variants and somatic mutations, RNA-Seq and miRNA-Seq derived gene and miRNA quantifications, and SNP Array based copy number segmentations.

  • December 16, 2015

The NCI GDC Completes Phase 2 Activities

The NCI's Genomic Data Commons (GDC) project completes Phase 2 activities. In Phase 2, the GDC provides support for data submission and harmonization to GRCh38, the latest reference genome build (GRCh38).

  • March 18, 2015

The NCI GDC Completes Phase 1 Activities

The NCI's Genomic Data Commons (GDC) project completes Phase 1 activities. In Phase 1, GDC provides support for TCGA datasets made accessible via the GDC Data Portal and the GDC Data Transfer Tool.

  • December 9, 2014

University of Chicago targets vast cancer data, will 'democratize' research

The Genomic Data Commons project will help researchers around the country assess genetic information from more than 10,000 cancer patients, which could be used to develop more effective treatments, said Robert Grossman, a professor of medicine at the University of Chicago who is directing the project.

  • December 2, 2014

NCI establishes Genomic Data Commons to facilitate identification of molecular subtypes of cancer and potential drug targets

The National Cancer Institute is establishing the NCI Genomic Data Commons (GDC) to store, analyze and distribute cancer genomics data generated by NCI and other research organizations. The GDC will provide an interactive system for researchers to access data, with the goal of advancing the molecular diagnosis of cancer and suggest potential therapeutic targets based on genomic information. The GDC is the first step toward the development of a knowledge system for cancer, as originally recommended in a 2011 Institute of Medicine (IOM) report, “Toward Precision Medicine.” 

  • December 2, 2014

Transforming Cancer Research: The Genomic Data Commons (Video)

The University of Chicago and the NCI are collaborating to establish the Genomic Data Commons (GDC). The GDC is a first-of-its-kind facility that will be the most comprehensive system to store data from NCI-funded research programs in a single repository, and harmonize them so they’re compatible. The GDC addresses a major issue in cancer research. A wealth of valuable tumor genome data has been collected by NCI-funded projects, but most researchers can’t make use of the material due to sheer size, disparate formats and dispersed storage locations. By bringing the data together in a single place, in a standardized format, the GDC will dramatically increase access to data for cancer researchers. Not only will this speed up the pace of cancer research, it will open new collaborations and serve as the foundation for future cloud-based research and open the door for new biomedical ecosystems such as personalized treatments for cancer.