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Accessing Genomic Data

The GDC Data Portal is a groundbreaking tool that enables a better understanding of cancer biology by allowing researchers to:

  • Search and query genomic data
  • Download data directly from the web browser or download large volumes of data using the high performance GDC Data Transfer Tool
  • Analyze cancer data including clinical information, genomic characterization data, and high level sequence analysis of the tumor genomes

Get Started by Exploring GDC Processes and Tools »

Data Access Tools

The GDC provides web-based tools and API endpoints for searching, viewing and downloading data as well as client tools for downloading large volumes of data.

Controlled Data Access Policy

Any user requesting access to GDC controlled data must apply for access to the data through the database of Genotypes and Phenotypes (dbGaP):

High Quality Datasets

The GDC obtains datasets from NCI programs which maintain tissue collection strategies that couple quantity with quality. Data validation is performed on all data submitted to the GDC.

What’s New with the GDC and Cancer Research

Cancer Research Highlights and Publications:

From the GDC FAQ

Why did the GDC remove SomaticSniper?

The SomaticSniper whole exome variant caller was one of the first generation somatic mutation callers developed by the scientific community. It works the best with blood cancer that has high level of tumor-in-normal contaminations, but is often overly permissive for solid tumors. Since our first data release in 2016, the GDC has gradually adopted newer tools or new tool versions, and has transited the focus of somatic variant calling from any single caller to multi-caller ensemble.

After comparing ensemble calls with and without SomaticSniper and also receiving feedback from the authors of SomaticSniper, the GDC decided to remove this tool from our production in Data Release 35. The GDC still maintains other four whole exome variant callers, including MuSE, MuTect2, Pindel, and VarScan2.

Need Assistance?

Need help with data retrieval, download, or submission?

Visit the GDC Support Page