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GDC Releases Data Release 43 with Expanded Genomic and Clinical Data

The GDC has announced Data Release 43, featuring a range of new and updated data sets. Key highlights from this release include: 

  • New Whole Genome Sequencing (WGS) Variants: New WGS variant calls for The Cancer Genome Atlas (TCGA) and other programs, featuring VarScan2 simple and annotated somatic mutations
  • Expanded HCMI Data: Adds WGS, Whole Exome Sequencing (WXS), and RNA-Seq data for 350+ additional cases from the Human Cancer Models Initiative (HCMI)
  • Clinical Data Enhancements: Updated clinical data for TCGA and the Clinical Proteomic Tumor Analysis Consortium (CPTAC) projects
  • BAM QC Metrics: New quality control metrics for sequencing alignments in BAM files

For a detailed list of updates, refer to the Data Release 43.0 Notes.