The Next Generation Cancer Knowledge Base

Cases by Major Primary Site

The NCI's Genomic Data Commons (GDC) provides the cancer research community with a unified repository and cancer knowledge base that enables data sharing across cancer genomic studies in support of precision medicine.

The GDC supports several cancer genome programs at the NCI Center for Cancer Genomics (CCG), including The Cancer Genome Atlas (TCGA) and Therapeutically Applicable Research to Generate Effective Treatments (TARGET).

High Quality Data Sharing Enables Precision Medicine

The GDC obtains validated datasets from NCI programs in which the strategies for tissue collection couples quantity with high quality.

The GDC encourages data sharing in support of precision medicine. Tools are provided to guide data submissions by researchers and institutions.


  • September 28, 2022

New TARGET AML RNA-Seq and CPTAC Single Nuclei RNA-Seq Data, Update to Variant Caller Pipeline

New data sets are now available including RNA-Seq data from the TARGET acute myeloid leukemia project and single nuclei RNA-Seq data from the CPTAC program. These changes are summarized below: ...
  • July 27, 2022

New Release of Beat AML Mutations, CPTAC Cases, and Fusion Data

In Data Release 34, the GDC released new data from the Beat AML and Clinical Proteomic Tumor Analysis Consortium (CPTAC) programs: Beat AML - Mutations and MAF files from the BEATAML1.0-COHORT ...