The Next Generation Cancer Knowledge Base

Cases by Major Primary Site

The NCI's Genomic Data Commons (GDC) provides the cancer research community with a unified repository and cancer knowledge base that enables data sharing across cancer genomic studies in support of precision medicine.

The GDC supports several cancer genome programs at the NCI Center for Cancer Genomics (CCG), including The Cancer Genome Atlas (TCGA) and Therapeutically Applicable Research to Generate Effective Treatments (TARGET).

High Quality Data Sharing Enables Precision Medicine

The GDC obtains validated datasets from NCI programs in which the strategies for tissue collection couples quantity with high quality.

The GDC encourages data sharing in support of precision medicine. Tools are provided to guide data submissions by researchers and institutions.


  • August 31, 2023

9000+ New TCGA WGS alignments Now Available!

The GDC’s Data Release 38 includes 9000+ high coverage TCGA WGS alignments, data for new CGCI, MATCH, and MP2PRT projects, and a variety of data from other NCI programs: 9000+ high coverage ...
  • June 16, 2023

New GDC Data Dictionary Clinical Properties for TARGET, HCMI, and TCGA

In GDC Data Dictionary Release 2.6.6, the GDC added support for: New Clinical Properties for TARGET, HCMI, and TCGA - Several new properties and enumerated values for diagnosis, treatment, ...