The Next Generation Cancer Knowledge Base

Cases by Major Primary Site

The NCI's Genomic Data Commons (GDC) provides the cancer research community with a unified repository and cancer knowledge base that enables data sharing across cancer genomic studies in support of precision medicine.

The GDC supports several cancer genome programs at the NCI Center for Cancer Genomics (CCG), including The Cancer Genome Atlas (TCGA) and Therapeutically Applicable Research to Generate Effective Treatments (TARGET).

High Quality Data Sharing Enables Precision Medicine

The GDC obtains validated datasets from NCI programs in which the strategies for tissue collection couples quantity with high quality.

The GDC encourages data sharing in support of precision medicine. Tools are provided to guide data submissions by researchers and institutions.


  • February 8, 2024

Introducing GDC 2.0: A New Cohort-Centric Design

The GDC has released GDC 2.0 which expands on the GDC Data Portal initially launched in 2016 by providing a cohort-centric design and new analysis tools. GDC 2.0 features include: Enhanced tools ...
  • December 4, 2023

New TCGA Whole Genome Data and Five New NCI MATCH Projects

GDC Data Release 39 is now available on the GDC Data Portal. Several main features for this release include new TCGA WGS variants and additional higher coverage alignments, and five new projects from ...