The Next Generation Cancer Knowledge Base

Cases by Major Primary Site

The NCI's Genomic Data Commons (GDC) provides the cancer research community with a unified repository and cancer knowledge base that enables data sharing across cancer genomic studies in support of precision medicine.

The GDC supports several cancer genome programs at the NCI Center for Cancer Genomics (CCG), including The Cancer Genome Atlas (TCGA) and Therapeutically Applicable Research to Generate Effective Treatments (TARGET).

High Quality Data Sharing Enables Precision Medicine

The GDC obtains validated datasets from NCI programs in which the strategies for tissue collection couples quantity with high quality.

The GDC encourages data sharing in support of precision medicine. Tools are provided to guide data submissions by researchers and institutions.


  • May 3, 2022

Exceptional Responders and MP2PRT: New NCI Projects at the GDC!

In Data Release 33, the GDC released data from two new projects at the GDC: NCI’s Exceptional Responders Initiative, which set out to understand why some patients have unexpected and long- ...
  • March 29, 2022

GDC Gene Model Updated to GENCODE 36

The gene model used as a reference across GDC has been updated from GENCODE 22 to GENCODE 36. GENCODE gene sets are continuously updated to improve the coverage and accuracy. GENCODE 36, which ...