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The Next Generation Cancer Knowledge Base

The Next Generation Cancer Knowledge Base
The Next Generation Cancer Knowledge Base
Cases by Major Primary Site
Data Availability Summary
Primary Sites

Launch Data Portal

The NCI's Genomic Data Commons (GDC) provides the cancer research community with a repository and computational platform for cancer researchers who need to understand cancer, its clinical progression, and response to therapy.

The GDC supports several cancer genome programs at the NCI Center for Cancer Genomics (CCG), including The Cancer Genome Atlas (TCGA) and Therapeutically Applicable Research to Generate Effective Treatments (TARGET).

High Quality Data Sharing Enables Precision Medicine

The GDC obtains validated datasets from NCI programs in which the strategies for tissue collection couples quantity with high quality.

The GDC encourages data sharing in support of precision medicine. Tools are provided to guide data submissions by researchers and institutions.


 GDC Data Dictionary 3.1 expands diagnosis information, TCGA properties, and bioinformatics workflows:

Introducing the latest advancements in GDC 2.0 with Release 2.1! Here's what's new:

GDC Data Release 40 is now accessible on the GDC Data Portal. This release introduces new data sets featuring additional TCGA WGS alignments and variant calls, WXS and RNA-Seq data for new NCI-MATCH Trial arms, and more. Below is a summary of the key highlights.