Analyze Data

Analyze Data

The GDC provides user-friendly and interactive Data Analysis, Visualization, and Exploration (DAVE) Tools supporting gene and variant level analysis that allows researchers to:

  • Visualize most frequently mutated genes and view most frequent somatic mutations for a project
  • Plot all cases for a project in an OncoGrid and visualize the top 50 mutated genes affected by high impact mutations
  • Perform a survival analysis for cases with a mutated form of a certain gene and cases without the mutation
  • Visualize mutations and their frequency across cases mapped to a graphical visualization of protein-coding regions using an interactive Protein Viewer
  • View the cancer distribution as evidenced by the number of cases affected by the mutation across all projects
  • Build cohorts and perform gene and variant level analysis on the cohort
  • Compare custom gene or case sets by visualizing set similarities and differences

Get Started by Exploring GDC Data Analysis Processes and Tools »

Illustration: Analyze Data

Documentation

GDC Data Portal User's Guide »

Data Analysis Tools

The GDC provides interactive tools supporting data analysis, exploration, and visualization.

Data Analysis Policy

The GDC provides policies for publishing the results of analyzed data.

Data Harmonization and Generation

GDC variant calling pipelines generate high level data for analysis. Variant calling pipelines are implemented using data processing software and algorithms selected in consultation with the expert genomics community.

What’s New with GDC and Cancer Research

Cancer Research Highlights and Publications:

From GDC FAQ

Why does the GDC display common genes such as TTN that are associated with every cancer in the most frequently mutated genes table?

The GDC is not normalizing frequency by gene length. This is currently under discussion. As such, these genes are appearing in the mutated genes table. Users can filter by the COSMIC Cancer Gene Census to display only genes for which mutations have been causally implicated in cancer.

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Need help with data retrieval, download, or submission?

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