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GDC Releases New NCI MATCH Trial Data, Whole Slide Images, and More in DR 41

GDC Data Release 41 is now accessible on the GDC Data Portal. This release introduces new data sets featuring data for new NCI-MATCH Trial arms, whole slide images, and more. Below is a summary of the key highlights. 

  • Genomic characterizations for the NCI MATCH Trial arms P, C1, and Z1B
    • MATCH-C1 – MET amplification (phs002177)
      MATCH-P – PTEN loss by immunohistochemistry (phs002152)
      MATCH-Z1B – CCND1, 2, and 3 amplifications and Rb protein expression by immunohistochemistry (phs002180)
  • scRNA-Seq data from the BEATAML Acute Myeloid Leukemia program
  • Whole slide images from the CDDP Integrative Analysis of Lung Adenocarcinoma (EAGLE) project
  • 31 new cases from the NCI’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) program
  • Methylation data from the TCGA Lung Adenocarcinoma (LUAD) project
  • U133 expression arrays for TCGA-GBM, TCGA-LAML, TCGA-LUSC, and TCGA-OV
  • Copy number variation data from ABSOLUTE available in the analysis tools
  • Data from the new "Other Clinical Attribute" node in the GDC API

For a comprehensive list of changes, please refer to the Data Release 41.0 Notes.