The GDC appreciates data donations from the following organizations:
Foundation Medicine, Inc. (FMI) is a molecular information company that specializes in precision medicine. FMI has generated genomic profiles for thousands of cancer patients, which are designed to match each patient to a personalized treatment plan.
The Multiple Myeloma Research Foundation (MMRF) is a non-profit organization with a mission to find a cure for multiple myeloma through precision medicine.
The National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) is a national effort to accelerate the understanding of the molecular basis of cancer through the application of large-scale proteome and genome analysis, or proteogenomics.
Count Me In (CMI) is a nonprofit research initiative that empowers patients to accelerate cancer research by sharing their samples, their clinical information, and their voices. A key goal of CMI is to enable scientific discoveries and the development of new cancer treatment strategies by widely sharing clinical, genomic, molecular, and patient-reported data.
The GDC provides access to several supported cancer research programs including TCGA, TARGET, and other contributing programs.
The Cancer Genome Atlas (TCGA)
The Cancer Genome Atlas (TCGA), a collaboration between the National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI), aims to generate comprehensive, multi-dimensional maps of the key genomic changes in major types and subtypes of cancer. TCGA has analyzed matched tumor and normal tissues from 11,000 patients, allowing for the comprehensive characterization of 33 cancer types and subtypes, including 10 rare cancers.
Therapeutically Applicable Research to Generate Effective Treatments (TARGET)
TARGET is the collaborative effort of a large, diverse consortium of extramural and NCI investigators. The goal of the effort is to accelerate molecular discoveries that drive the initiation and progression of hard-to-treat childhood cancers. and facilitate rapid translation of those findings into the clinic.
Cancer Genome Characterization Initiatives (CGCI)
The CGCI program supports cutting-edge genomics research of adult and pediatric cancers. CGCI investigators develop and apply advanced sequencing methods that examine genomes, exomes, and transcriptomes within various types of tumors.
Human Cancer Model Initiative (HCMI)
HCMI is a collaborative international consortium that is generating novel, next-generation, tumor-derived culture models annotated with genomic and clinical data. HCMI-developed models and related data are available as a community resource.
Other Contributing Programs
Data from other supported programs is submitted to the GDC in standard data formats through the GDC Data Submission Pipeline. As the GDC continues to provide support for new programs of diverse cancer types, please refer to the lists of programs and associated cancer types in the following:
Collaborating with GDC
The GDC encourages data sharing in support of precision medicine. Tools are provided to guide data submissions, however, for more information contact the GDC Help Desk:
For assistance with GDC query, download and submission of data, please contact the GDC Help Desk (support@nci-gdc.datacommons.io).
Submitting GDC support requests requires the submission of Personally Identifiable Information (PII). Please see the GDC Privacy Policy and GDC Privacy Act Notification for additional information.
GDC responses to information requests are reviewed daily, and resolution is provided in the timeliest manner possible.