Main Content

Access Data

Why do some genes show no expression in STAR results across all samples, even though I can see mapped reads in the raw RNA-Seq data?

Submitted by gaheens on

STAR gene expression quantification excludes reads that are mapped to multiple different genes. This can cause some genes to appear with zero expression in the final counts, even if mapped reads are present in the raw data. 

In the GDC Data Portal, when I filter by Experimental Strategy (e.g., RNA-Seq) in the Cohort Builder Available Data filter, why is this filter not working when I navigate to Repository?

Submitted by gaheens on

Filtering in Cohort Builder results in a set of cases. Cases typically have available data for multiple Experimental Strategies (e.g., cases with RNA-Seq data can also have DNA-Seq data). As such, when navigating to Repository additional data besides RNA-Seq data is displayed. Repository filters are file based. When filtering Repository by Experimental Strategy (e.g., RNA-Seq) only files associated with the Experimental Strategy are displayed.

Subscribe to Access Data