Access Data

TCGA clinical data was expanded in GDC Data Releases 42 and 43. TCGA clinical data used to have one diagnosis per case. With the clinical data expansion, it is possible that a TCGA case has multiple diagnoses. This could be due to pre-enrollment diagnoses or other reasons. To properly query for the diagnosis information associated with the molecular data, the primary disease flag should be set to true (i.e., diagnosis_is_primary_disease = true).

The GDC Turing Data Dictionary Release 3.4 includes the following features:

The GDC has announced Data Release 43, featuring a range of new and updated data sets. Key highlights from this release include: 

It may take up to 24 hours for the GDC to sync with dbGaP. Please allow this time after receiving dbGaP authorization before attempting to access the study’s data on the GDC.

The GDC 2.4 Röntgen Release brings a range of new features aimed at enhancing data analysis and user experience.

STAR gene expression quantification excludes reads that are mapped to multiple different genes. This can cause some genes to appear with zero expression in the final counts, even if mapped reads are present in the raw data. 

The GDC is excited to announce the release of 8000+ new whole genome sequencing (WGS) variant calls as part of Data Release 42. Highlights of this release include:

The latest GDC 2.3 Pauling Release introduces several new features designed to enhance user experience and improve data analysis.

GDC Data Dictionary

New GDC Data Dictionary properties were added in the Okazaki release. Key highlights include:

Filtering in Cohort Builder results in a set of cases. A case can have multiple diagnosis and tissues or organ of origins may be related to a secondary diagnosis.