Access Data

The Genomic Data Commons strives to provide standardized and relevant genomic data to the cancer research community.

The GDC’s Data Release 37 includes four new projects: APOLLO-LUAD - Proteogenomic Characterization of Lung Adenocarcinoma, CGCI-HTMCP-LC - HIV+ Tumor Molecular Characterization of Lung

In GDC Data Dictionary Release 2.6.0, the GDC added support for:

GDC Data Release 36 includes WXS and RNA-Seq data for cases from NCI’s MATCH precision medicine clinical trial (MATCH-Z1D; phs001859) and WGS, WXS, and RNA-Seq data for lung adenocarcinoma cases fr

Generally any WGS data should have associated structural variant files (BEDPE) except in the cases in which either there are no tumor/normal matches or when variant calling has not been implemented yet.

The SomaticSniper whole exome variant caller was one of the first generation somatic mutation callers developed by the scientific community. It works the best with blood cancer that has high level of tumor-in-normal contaminations, but is often overly permissive for solid tumors. Since our first data release in 2016, the GDC has gradually adopted newer tools or new tool versions, and has transited the focus of somatic variant calling from any single caller to multi-caller ensemble.

New data sets are now available including RNA-Seq data from the TARGET acute myeloid leukemia project and single nuclei RNA-Seq data from the CPTAC program. These changes are summarized below:

In Data Release 34, the GDC released new data from the Beat AML and Clinical Proteomic Tumor Analysis Consortium (CPTAC) programs: