General GDC

HIPAA guidelines require that patients with ages greater than 89 years be aggregated into a single age category. This is to limit the ability to positively identify these individuals. In practice this will impact the values reported in several fields. We have chosen to accurately display the age at diagnosis, but fields that give dates or time periods after this benchmark may be compressed. This may include such fields as "Days to last follow up", "Days to last known disease status", "Days to recurrence", "Days to death", and "Year of death".

The NCI’s Genomic Data Commons (GDC) project completes Phase 3 activities.

Recurrent data releases allow the GDC to version the data and allow users to reference the GDC version number in publications. GDC currently generates releases as needed, with a release every 2-3 months as a goal.

Submitted BAM files are validated at the GDC for file integrity and format using md5sum checks, automated QC checks, and the Picard ValidateSamFiles tool. Sequencing quality is assessed using FASTQC, and additional quality metrics are gathered using tools like Picard and Samtools. Severe issues, such as high cross-sample contamination, may prevent the data from being released, but minor issues typically do not result in rejection. Instead, the GDC exposes many of the quality metrics so users may review them and do further filtering.

The NCI's Genomic Data Commons (GDC) project completes Phase 2 activities.

GDC scheduled maintenance is typically performed during weekends. GDC maintenance is sometimes performed during weekdays in the evenings for security patches, when needed.

The Genomic Data Commons project will help researchers around the country assess genetic information from more than 10,000 cancer patients, which could be used to develop more effective treatments,

The NCI's Genomic Data Commons (GDC) project completes Phase 1 activities.

The University of Chicago and the NCI are collaborating to establish the Genomic Data Commons (GDC).

The National Cancer Institute is establishing the NCI Genomic Data Commons (GDC) to store, analyze and distribute cancer genomics data generated by NCI and other research organizations.