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Pan-cancer genome and transcriptome analyses of 1699 paediatric leukaemias and solid tumours

Nature. Volume 555(7696): p.371-376, 15 March 2018, 10.1038/nature25795

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Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group

Clin Cancer Res. Volume 22, Issue 22: p.5582–5591, 4 October 2016, 10.1158/1078-0432.CCR-16-0985

PURPOSE: To investigate the role and significance of TP53 mutation in diffuse anaplastic Wilms tumors (DAWTs). EXPERIMENTAL DESIGN: All DAWTs registered on National Wilms Tumor Study-5 (n = 118) with available samples were sequenced (either WGS or WXS, when possible mRNA-seq). The data was analyzed for TP53 mutations and copy loss and in 39 cases the genomic data was integrated.

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MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours

Nat Commun. Volume 6: 10013, 4 December 2016, 10.1038/ncomms10013

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Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors

Cancer Cell. Volume 27, Issue 2: p.286-297, 9 February 2015 10.1016/j.ccell.2015.01.003

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A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor.

Nat Genet. Volume 49, Issue 10 p.1487-1494, 21 August 2017 10.1038/ng.3940

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