NPJ Precis Oncol. Volume 8, Issue 1: 68. March 13, 2024 10.1038/s41698-024-00519-8
APOLLO is a proteogenomic study seeking to describe the major genome, transcriptome, proteome and phosphoproteome alterations, subtypes, and molecular predictors of patient outcomes. This study includes 70 high grade serous ovarian carcinoma tissues from the Gynecologic Cancer Center of Excellence (https://medschool.usuhs.edu/gso/research/gyn-cancer-center-of-excellence). Bulk and laser microdissection enriched tumor tissues were profiled by whole genome sequencing, transcriptome sequencing, MS-based proteomics and reverse phase protein arrays. Clinical and sample data include survival times, patient features, and tumor characteristics.
Data in the GDC
- GDC Supplemental Manifests
- Open-Access Data - Download Manifest (9 Files)
Supplemental Data
- APOLLO-OV_WholeTumor_GlobalProteomics_raw.csv - Whole tumor - Global proteomics data
- APOLLO-OV_WholeTumor_GlobalProteomics_imputed.csv - Whole tumor - Global proteomics data - imputed
- APOLLO-OV_EnrichedTumor_GlobalProteomics_raw.csv - Enriched tumor - Global proteomics data
- APOLLO-OV_EnrichedTumor_GlobalProteomics_imputed.csv - Enriched tumor - Global proteomics data - imputed
- APOLLO-OV_EnrichedStroma_GlobalProteomics_raw.csv- Enriched stroma - Global proteomics data
- APOLLO-OV_EnrichedStroma_GlobalProteomics_imputed.csv - Enriched stroma - Global proteomics data - imputed
- APOLLO-OV_EnrichedTumor_RPPA.csv - Enriched tumor - RPPA data
- APOLLO-OV_WholeTumor_RNASeq_NormalizedCounts.csv - Whole tumor - RNAseq data
- APOLLO-OV_EnrichedTumor_RNASeq_NormalizedCounts.csv - Enriched tumor - RNAseq data